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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1e9dfaa4df0052d0601562e663b95875f169abe9c5876fdf94d86396e021e46' 
  AND token = 'G8PfIQZhQHu0ff+YQQF+aMFbvE4k++MCUTBpF3HgXJ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}