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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de2e2c0d28be86f64e4c1794db49a92e575b3b6099329dba22f855a4a2db4eff' 
  AND token = 'YEz19Ri37g2aqwUo2k/bQwT1XhZjBr8M+j2f5tYjqYU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}