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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61110456aad2c74271c3e32cac6fa0d476003a816866d047c21200ddbc5b1af1' 
  AND token = 'wK09h8dd0t6csXV3q/tfGZe63YgBf7XIxKhe8dwDfOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}