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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f47af9bd90374a65c1e8bc74fc4552ccc4b90b2b101fcb15ba9a6f92168716a' 
  AND token = 'jIRS8fHikCUU3k7MXDGkDCh+4J1s9wuRk1L3rhE/iiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}