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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c8f5563a8bd3f02495f4bf50a3b2dc190af03d5982b20e05732e132cc3ed2ed' 
  AND token = 'nMdFgpujj2hEiq52pvA6brRrl8y69lCARAc0maXjoI4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}