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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dd0e6bfa53635b4f21bb335659cbc745bc38721f6263e7c49cf6b86fcb49e35' 
  AND token = 'zXEqsHkKlO4/8O+Mfq4Xp9QzLL1ZPJc97KSaJowcnsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}