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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dbc06465be79c2cda6139cabfa1183b4bebb15678fbbafe6b1df5b13e9d1fa6' 
  AND token = '2cB54p0Vlj6vjewbab4gSJ5ORCB4L366Gg6I2PmrcyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}