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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc428db69e62511d61657d9f1d3b9ea36056be3dd1dfa8820529a1dd561414a2' 
  AND token = 'jx7bvpEKrsG+2jLe/2lSIL4+i3zG5piwNNlCAUM4Ldw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}