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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ff1707dbde220f451cd07de9675b401997ea9d11909e7c1484d4b8ba6219a2' 
  AND token = 'mEG1+REvYS03rj0VHErucvvg/65gW0hl7NUx2oLvYLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}