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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc39c8e4ffdc1c174b4346951edbc0f3046800bcf8a9b2ab97845e93585dc623' 
  AND token = '4ifDJweOUjmN6MiCO6xpYS36BdixQrlVY2X8RQwP0MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}