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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb19ae1b9c3cf399a4cde82ab460b3b6659a6d4621382f3e3138dbb746dc125' 
  AND token = '1XTAGUW5+qka8qkxXjHxKemarxpTeyJszo23hns8/Wg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}