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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66b9f861425eac5a777308d19a6231c4d2499163939cf997c47d76800f9363b' 
  AND token = 'ONkh0aKS4AykPp5fZYy8d9W6K7MvJXZEJBDdDv67hbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}