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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bb4569a69e659b74c508364ac933942f9bf9b9247edae12417b7ac45d442b66' 
  AND token = '3E6uRt/A+XULt2g45ATWN19oe95W0+AGDjNBq3BSa5A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}