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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f387c518f751db00a02b64f76d2e0aef61a69b806e5c700f078e2faea1d5c14' 
  AND token = 'DSD4xPAavLQkP8C/rjZ3bizyoefdRVE1JTO67pzOrTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}