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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c1c209f94cad1ed74514bdcb48f55448b2a414191d440cdc1f0d32509c457a8' 
  AND token = 'UyliLIvsRay/NLbgYMwrqMj780Rxb11oJnbGoaf9Z/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}