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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b1f80eb9cc1f2fe7252956006415ffad7cf782620e56b722fe566696eb5a5bb' 
  AND token = 'GHiFKGrtuHL1lEDT+ogS/Zb0q6OMWp/zY66Bb7bKTgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}