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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8a1e02af7cb34aa7e1a4f4fe5945ead942e350297df9958f631a4131517e12' 
  AND token = '1lDsF5oY1dhlZ8BkDt/wVOtaO10GE9MyACKuh2TVH5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}