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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eb2009555d27057e6b9f046cca8ef1c4d6778b1aa5f3ebf51578163980c0573' 
  AND token = 'u9AeuSsrohp54WfT6C3LUsMqR1pXVhtosM3ubAoxvYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}