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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '425622eca531d29414f676db4aecbc8a7906e65e73a833886e6bca85020bbb7b' 
  AND token = '8r3xArEOZvMTzALl1Kamd0+8tLkdOgmg4W98ZFDKjCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}