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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0dfdeb91551786cb708a2a1ee23348dda65bd50b3fd10a26299de27caebde66' 
  AND token = 'q266dxi4+rYOFLTHDf9f+ghSvRIEhacQcXqz3AeC+Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}