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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a50b4f596775735c8a18954e8988c93c9a1f8ba349401cf66f54e77a571386a1' 
  AND token = 'F6wYUsemiRu46WK5HKfOzXUXCczDYDS2tOF1PRzsz/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}