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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b36afada27ac3668a07cf33882c4b83c943acfc7f22cb9bf821b7089505d72d8' 
  AND token = 'C+cY+kbHrRoxzTy7XX5lhorIAuyBkE6JgwzL5eSeitM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}