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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad99be0979195970921ebdeaebf6a18deae79df5ee3c6e157876d2bb8a6fef2' 
  AND token = 'CPT98V/MM/TB0DC521aeIe4fxWKJkjqLVmdMCmLe+3E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}