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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8f47d4c04d26cb66074217c2390e01d95a1cdcac642830193187ad316fa6086' 
  AND token = 'IM8WfRM5BDfp+1v2B24ekYEWr8Ppirh9AemxeXOGEEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}