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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0614dce6741b2ee3452ea517f97c1afbf1b4eddaa1835a5be18ba46b5db12c61' 
  AND token = 'HtjH7dWwDPYQ6z/tnbQaKLGtxpxH38Ma+Nr2HnW1tj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}