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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa2595d959a2926f642f9cb1dee43a7230ff259665af7e999d8202b463f12bfa' 
  AND token = 'e7czxMJXeaGyaRHY7VuFXAmlK3/66R6xRlyvrSw8nGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}