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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450aa838ff97439742131a5a93ab85e9f3730d1e273800467073f5b639e30f37' 
  AND token = '+L2itz4QEA7ydiEGg8yZh37urfddmh3KSzUs5F8Ecjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}