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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '849613c99d6761f6b8d2a21fa076f9caa12f66d54cbf0b891486a60051abee86' 
  AND token = '6qKzihxsq35WTeE40jPaOddWSgHLM8AUDdLqAljkowY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}