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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79243d811198044da7a22e4bf9414fa6db18d2c0d7b67554ed16f3a850c2b6e6' 
  AND token = 'C5P66Sm6Tyufhpl2ngmE6jZpJMyJJxepAA4syfYgl5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}