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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353beeb8c45d577838bd1b98be34e1a39f0ec6c0045a7f1c07b9f14f8cad21d8' 
  AND token = 'gRM7Mm4V/Ge8wS51UgPDTR0Uu9E0yChzZG+Hqdx9Lz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}