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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0481c298f72eaaeef92698bae2cfef77c8b5ac8640fa0025f6ca906f3d53d110' 
  AND token = 'H+IO4Ej21bTy1q3QRE9+qMzp1VSz5cDo9VrHwnUfY4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}