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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac0975586f1c430d0cb66b48be6c3230656b4e09095e3dd8d9933b0b41dbd54' 
  AND token = 'P/MQ6jBk+hevkWTGVSVj60IatCv2v7luni0Lqx+Bjds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}