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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3188fe7ee2f03f38fa18d615bc490c4c3bce40624ed46227aa670c87ca87ad3d' 
  AND token = '4zj7Ayb84A/B4UJUU+SEXZFkQadhFw+Xk2Ia4bVKalc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}