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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2486f1cc5f3b51ded1917a01e361f70255ae0fa504aa6324576b74e8b02a48cd' 
  AND token = '7RjrbveU7IRESse0SM5RwBhqb04GsdRD+4G7MmumyjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}