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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2212245014512cdd2e2a2dcc5fc51a9e0ce6d34f6b06f52c505200a9fa4e37b' 
  AND token = 'T6YZjl5QGFaJ53zUGQpeEaL1HQaof5MzgpNPeh0/BZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}