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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4521b2c9162d08fdeb5a2b3f851edaa6324dce18d3e2f032dde05450dfafc7a' 
  AND token = 'jEd2GR4MszWXaZ1YOvuTrHZJ/VTT4qZjF8zrmQZApiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}