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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6df7917bda8f4fc6f8c743496bb280d87aeb53eed88ee456e543e45bc31f87' 
  AND token = 'ZCnVF/BCK8yCBkdeSD/8yc6vT5xh58elw8zgKk49JfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}