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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d6c439c1e0cf7bbb151b44b2540faaac20c74dc4c8607e9373c25702655ae04' 
  AND token = 'MFLZs0bL6YR4vRJu9+9uA/9RDhbYYmXR6kL1r6nQKO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}