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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e9d3c82ef30bf2c30d84dc999dd017eea87fae82b5e9f8f2e49559614df15c8' 
  AND token = 'PffAvMHUV80ckoN8/i6ioMcK9UQ27zJRDSm1hC0BhdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}