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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f559c32db3ac998b1cc6a3ec6f6b3d339e7daa389992f5769fd74b483e26c333' 
  AND token = 'NB0+wb8ftkFxAfFpVtRsY0gZRg99+f4wzDjFPqw+7Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}