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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c88c455fb3827e01fcf9b357a7cc1488cb8f012394d82c2e639890920db4962' 
  AND token = 'byrfRXzwGlK50iruZbW4APJdNEUIUN87K6VuCs3w9ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}