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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb8d47c7403e29d8554f0ac16de4b7cd5808122d2bcf6108bd8e46942a15773' 
  AND token = 'yUL/Tir2ozZfQd2l1xHjBju1bQXVrVB+sjdG0DPboDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}