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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22fee357f5dd2f6584242975d540581d2ae3bc22cb315a1293c82f008bc7d92a' 
  AND token = 'TCpCRkuYKOS6o1lzFPD5C515woGKPLkJHvGUaAZAi3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}