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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a94b916f825901a9b8eb697f4a14b81f51ba9c4a4207bdfda7959c631bb5e1f9' 
  AND token = '0DAxHZpBz4tTNgOLwjtLdyo5vb9ER7k/tL0u9EZ00Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}