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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d10d6e24e0c474a97acbb9520e1251e4634ac8c3bc7dc71da6fb06f5a028224' 
  AND token = 'XbOiF/ExbvSUVZ3MzqYwel0QgYRuitVlDcm0iKVNUwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}