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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67973f8f27f1ea257b31b03e72bf0b489bc37c1f1aacab4848b56c20919659f4' 
  AND token = 'i8xMDnKXaYkMvGWi4QoLWsZpQ1RDabUvcHXzH0rSZoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}