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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c9381080500defd25d01cc980493f3e4a1d9db99d082dcd84647abae1cf34a0' 
  AND token = 'fzdG6MUYW6+Vo3peI3qIwar9X9XZHB6d58xCvyQ46BI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}