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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52146a2ae5e054be4b7a113fd838564f87543307a447fc3cb4bf6b6831e985d0' 
  AND token = 'NMSUdQvlVVCSdP9ehppAwJjNN4Q+DhNUuA1lZ/MfaiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}