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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64527398079fd16dd8a99d0a1dd035408524571ef86654258486e4de5d43c9dd' 
  AND token = '4kjHFGFzX1GyXiMsHYOVYh5Nt9TtEbo+Z3T7MZ95b2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}