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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5c2980e915bf2f6195d10b07dca6cc6f918aa56fabde7fe2584a4caabacdfc5' 
  AND token = 'N465h0OUKe/g9evqTfW1Lh4Gna+xbMKR3vAvVYW3q8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}